NEWS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF KAZAKHSTAN. SERIES OF BIOLOGICAL AND MEDICAL

• N. А. Abilkayir

APPLICATION OF CONTENT MANAGEMENT SYSTEM BY EXAMPLE OF MUNICIPAL CLINIC        5-11

• D. R. Kaidarova, K. K. Smagulova, Zh. Zh. Zholdybay, Zh. K. Chingissova

KRAS MUTATION FREQUENCY AND SPECTRUM IN COLORECTAL CANCER: CORRELATION WITH THE TUMOR LOCALIZATION IN KAZAKHSTANI POPULATION         12-16

• I. A. Ratnikova, N. N. Gavrilova, Zh. E. Sagidoldina

CREATION OF A PROBIOTIC OF A BROAD SPECTRUM OF ACTIVITY ON THE BASIS OF LACTIC ACID AND PROPIONI ACID BACTERIA        17-23

• A. K. Rakhmetullina, A. T. Ivashchenko

RICE miRNAs ARE POTENTIAL REGULATORS OF HUMAN GENES EXPRESSION        24-31

• E. D. Dzhangalina1, 2, E. A. Shadenova1 , M. A. Kaigermazova1 , A. A. Mamirova1, 2, B. A. Zhumabayeva 2

PROSPECTS FOR THE USE OF TREE CROPS IN THE PHYTOREMEDIATION OF SOILS CONTAMINATED WITH HEAVY METALS AND PESTICIDES (review)      32-42

• P. S. Dmitriyev, T. N. Lyssakova

PROSPECTS AND THE CURRENT STATE OF THE LAKE AND COMMODITY FISHING OF THE NORTH KAZAKHSTAN REGION        43-46

• А. Okasov1 , А. Kalimagambetov2 , N. Akhmatullina1 , А. Ilin1

In vitro PROTEOLYTIC ACTIVATION OF CARCINOLYTIC PARASPORAL INCLUSIONS OF Bacillus thuringiensis ssp. israelensis BACTERIA         47-54

• Z. Z. Sayakova1 , V. P. Sadovskaya1 , A. B. Yeszhanov1 , V. G. Meka-Mechenko1 , T. N. Kunitsa1 , M. V. Kulemin2 , I. B. Kim3

DISTRIBUTION OF TICKS OF THE GENUS DERMACENTOR KOCH, 1844 (IXODIDAE, AMBLYOMMINAE) IN THE SOUTH-EASTERN PART OF KAZAKHSTAN        55-62

• А. Okasov1 , S. Kitada2 , А. Kalimagambetov3 , N. Akhmatullina1 , А. Ilin1

In vitro COMPARABLE ANALYSIS OF CARCINOLYTIC ACTIVITY OF MUTANT PROTEIN PARASPORIN-2 ON THE HUMAN HEPATOCARCINOMA CELL MODEL       63-71